Assessment of tumor markers CA 19-9, CEA, CA 125, and CA 242 for the early diagnosis and prognosis prediction of gallbladder cancer

Table 8 Correlations between carbohydrate antigen 19-9, carcinoembryonic antigen, carbohydrate antigen 125, and carbohydrate antigen 242 expression and lymph node metastasis

Marker level	No LNM, n = 36	LNM, n = 44	P value
CA 19-9 in U/mL	110.5 (54.2- 176.7)	221.8 (14.9-753.0)	< 0.05
CEA in µg/L	3.2 (1.4-4.0)	3.37 (1.9-6.2)	> 0.05
CA 125 in U/mL	23.0 (21.5-47.3)	33.0 (7.4-64.2)	> 0.05
CA 242 in U/mL	48.5 (36.1-84.7)	92.0 (25.8-112.0)	< 0.05

Data shown as median (interquartile range). Test: Independent sample t-test. CA 19-9: Carbohydrate antigen 19-9; CA 125: Carbohydrate antigen 125; CA 242: Carbohydrate antigen 242; CEA: Carcinoembryonic antigen; LNM: Lymph node metastasis.