Finding the seed of recurrence: Hepatocellular carcinoma circulating tumor cells and their potential to drive the surgical treatment

doi:10.4240/wjgs.v13.i9.967

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Sep 27, 2021; 13(9): 967-978
Published online Sep 27, 2021. doi: 10.4240/wjgs.v13.i9.967

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Figure 1 Hepatocellular carcinoma releases tumor cells into circulation where they become circulating tumor cells. Circulating tumor cells after evading the immune system can cause hepatocellular carcinoma recurrence or distant metastasis. The liquid biopsy intercepts these cells into the bloodstream and allows to study the tumor characteristics and guarantee personalized therapy. CTCs: Circulating tumor cells; HCC: Hepatocellular carcinoma.

Citation: Carissimi F, Barbaglia MN, Salmi L, Ciulli C, Roccamatisi L, Cordaro G, Mallela VR, Minisini R, Leone BE, Donadon M, Torzilli G, Pirisi M, Romano F, Famularo S. Finding the seed of recurrence: Hepatocellular carcinoma circulating tumor cells and their potential to drive the surgical treatment. World J Gastrointest Surg 2021; 13(9): 967-978
URL: https://www.wjgnet.com/1948-9366/full/v13/i9/967.htm
DOI: https://dx.doi.org/10.4240/wjgs.v13.i9.967

Carissimi F, Barbaglia MN, Salmi L, Ciulli C, Roccamatisi L, Cordaro G, Mallela VR, Minisini R, Leone BE, Donadon M, Torzilli G, Pirisi M, Romano F, Famularo S. Finding the seed of recurrence: Hepatocellular carcinoma circulating tumor cells and their potential to drive the surgical treatment. World J Gastrointest Surg 2021; 13(9): 967-978 [PMID: 34621473 DOI: 10.4240/wjgs.v13.i9.967]

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