Closure techniques in exposed endoscopic full-thickness resection: Overview and future perspectives in the endoscopic suturing era

Table 3 Summary of studies reporting post-endoscopic full-thickness resection defect closure by the use of over-the-scope clips

Ref.	Study design	Lesions, n	Mean tumor size (range), cm	Site (cardia/antrum/ body/fundus)	R0	Surgical conversion	Suture technique	Suture technical success	Mean operation time (range), min	Mean suture time (range), min		Major adverse events
Guo et al[25], 2015	R	23	1.21 ± 0.47 (0.6-2.0)	0/3/9/11	23	0	OTSC	23	40.5 ± 25.8 (16–104)		4.9 ± 2.2 (2–12)	0
Wang et al[26], 2019	CS	2	1.1 (1-1.2)	0/0/1/1	2	0	OTSC	2	108.5 (48-121)		43 (16-70)	0
Hu et al[27], 2020	R	20	2.4 ± 0.26 (-)	0/0/0/20	20	0	OTSC +/- clips	20	130.6 ± 51.9 (-)		-	0

R: Retrospective; OTSC: Over-the-scope clip; CS: Case series.