Combination of preoperative fibrinogen and D-dimer as a prognostic indicator in pancreatic ductal adenocarcinoma patients undergoing R0 resection

Figure 2 Receiver operating characteristic curve for overall survival analysis according to the preoperative fibrinogen concentration and preoperative D-dimer concentration. A: The area under the receiver operating characteristic (ROC) curve (AUC) was calculated to show the diagnostic ability of preoperative fibrinogen. In this model, the optimal cutoff value of the preoperative fibrinogen concentration was 3.31 g/L, and the AUC was 0.714 (95%CI: 0.649-0.779), while the sensitivity and specificity at the maximal Youden's index were 61.14% and 79.37%, respectively; B: The optimal cutoff value of the preoperative D-dimer concentration was 0.52 mg/L, and the AUC was 0.753 (95%CI: 0.687-0.819), while the sensitivity and specificity at the maximal Youden's index were 58.78% and 78.82%, respectively.