Gastroenteropancreatic neuroendocrine neoplasms: A clinical snapshot

Table 1 The enteroendocrine cells, secretory products, and their physiological functions[3,4]

EECs	Amine/peptide hormones	Physiological functions of the hormones
ECs	Serotonin	Regulation of appetite and gut motility
ECLs	Histamine	Regulation of gastric acidity
L-cells	GLP-1, GLP-2, peptide YY, glicentin and oxyntomodulin	Regulation of appetite, gut motility, and insulin kinetics
K-cells	GIP	Insulin kinetics
D-cells	Somatostatin	Regulation of gastric acidity, and insulin secretion
A-cells	Ghrelin and nesfatin-1	Regulation of appetite and growth hormone
G-cells	Gastrin	Regulation of gastric acidity
P-cells	Leptin	Regulation of appetite
S-cells	Secretin	Regulation of gastric acidity
I-cells	CCK	Modulation of appetite, gall bladder motility, and bile release
M-cells	Motilin	Regulation of gut motility
N-cells	Neurotensin	Regulation of gut motility

CCK: Cholecystokinin; EECs: Enteroendocrine cells; ECs: Enterochromaffin cells; ECLs: Enterochromaffin-like cells; GLP: Glucagon-like peptide; GIP: Glucose-dependent insulinotropic polypeptide.