Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 13, Issue 2

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Gastrointest Surg. Feb 27, 2021; 13(2): 164-175
Published online Feb 27, 2021. doi: 10.4240/wjgs.v13.i2.164

Table 3 Immunohistochemical and molecular phenotypes

Molecular or immunohistochemical feature	CRC patients < 50 yr of age, n (%)	CRC patients ≥ 50 yr of age, n (%)	P value
Microsatellite stability
Stable	56 (91.8)	213 (84.9)	0.21
Unstabile	5 (8.2)	38 (15.1)
NA	9	90
KRAS mutation
Negative	23 (65.7)	48 (51.1)	0.17
Positive	12 (34.3)	46 (48.9)
NA	35	247
NRAS mutation
Negative	27 (90)	74 (94.9)	0.39
Positive	3 (10)	4 (5.1)
NA	40	263
BRAF mutation
Negative	29 (90.6)	87 (86.1)	0.76
Positive	3 (9.4)	14 (13.9)
NA	38	240
HER 2
Negative	8 (80)	24 (70.6)	0.70
Positive	2 (20)	10 (29.4)
NA	60	307

CRC: Colorectal cancer; NA: Not available.

Citation: Mueller M, Schneider MA, Deplazes B, Cabalzar-Wondberg D, Rickenbacher A, Turina M. Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study. World J Gastrointest Surg 2021; 13(2): 164-175
URL: https://www.wjgnet.com/1948-9366/full/v13/i2/164.htm
DOI: https://dx.doi.org/10.4240/wjgs.v13.i2.164

Mueller M, Schneider MA, Deplazes B, Cabalzar-Wondberg D, Rickenbacher A, Turina M. Colorectal cancer of the young displays distinct features of aggressive tumor biology: A single-center cohort study. World J Gastrointest Surg 2021; 13(2): 164-175 [PMID: 33643536 DOI: 10.4240/wjgs.v13.i2.164]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.