Novel roles of lipopolysaccharide and TLR4/NF-κB signaling pathway in inflammatory response to liver injury in Budd-Chiari syndrome

Table 6 Levels of lipopolysaccharide and TLR4/NF-κB-mediated inflammation-related indicators in the blood samples from human subjects

	LPS (Eu/mL)	TLR4 (%)	NF-κB (pg/mL)	IL-2 (pg/mL)	TNF-α (pg/mL)	IFN-γ (pg/mL)
Control group	8.42 ± 2.33	5.05 ± 1.29	8.15 ± 1.65	21.19 ± 5.01	24.88 ± 4.07	16.60 ± 1.80
Chronic group	20.96 ± 6.70	14.00 ± 3.67	28.75 ± 4.17	65.62 ± 13.26	46.68 ± 7.55	35.87 ± 7.36
Acute group	34.44 ± 10.45a,b	24.55 ± 7.0a,b	65.17 ± 11.09a,b	127.90 ± 26.57a,b	77.88 ± 9.61a,b	70.90 ± 11.95a,b
F	95.541	132.171	524.000	285.085	384.673	340.340

^aP < 0.05, Acute group vs Chronic group, the differences are statistically significant.

^bP < 0.05, Acute group vs Control group, the differences are statistically significant.

LPS: Lipopolysaccharide; TLR4: Toll-like receptor 4; NF-κB: Nuclear factor-κB; TNF-α: Tumor necrosis factor-α; IL-2: Interleukin-2; IFN-γ: Interferon-γ.