Low serum albumin may predict poor efficacy in patients with perforated peptic ulcer treated nonoperatively

Table 4 Logistic regression analysis of predictors of clinical complications in patients with perforated peptic ulcer

Variables	OR	95%CI	P value	Adjusted OR	95%CI	P value
Age ≥ 70 yr	2.331	1.277-4.254	0.006	1.630	0.853-3.114	0.139
Male	1.390	0.777-2.488	0.268
Hypertension	1.008	0.528-1.928	0.980
Diabetes mellitus	1.729	0.842-3.550	0.136
Smoking status	0.757	0.432-1.328	0.331
Alcohol consumption	0.970	0.527-1.785	0.922
NSAIDs use	0.977	0.519-1.839	0.941
Pain duration prior to admission ≥ 12 h	1.316	0.667-2.594	0.428
Heart rate	1.005	0.988-1.023	0.568
Body temperature ≥ 38 C	0.586	0.214-1.606	0.299
Hemoglobin < 90 g/L	0.590	0.236-1.471	0.257
WBC count ≥ 12 × 109/L	0.787	0.441-1.405	0.418
Procalcitonin	1.021	0.994-1.048	0.126
CRP	1.000	0.999-1.001	0.933
Serum albumin < 30 g/L	3.376	1.917-5.946	< 0.001	2.945	1.625-5.339	< 0.001

CRP: C-reactive protein; NSAIDs: Non-steroidal anti-inflammatory drugs; PPU: Perforated peptic ulcer; WBC: White blood cell.