Long-term survival outcome of laparoscopic liver resection for hepatocellular carcinoma

Table 4 Summary of comparative studies: Long-term oncological outcomes

Ref.	1-year OS, %			3-year OS, %			5-year OS, %			1-year DFS, %			3-year DFS, %			5-year DFS, %
	LLR	OLR	P	LLR	OLR	P	LLR	OLR	P	LLR	OLR	P	LLR	OLR	P	LLR	OLR	P
Belli et al[5]	94	85	NS	67	53	NS				78	79	NS	52	52	NS
Tranchart et al[6]	93.1	81.8	NS	74.4	73	NS	59.5	47.4	NS	81.6	70.2	NS	60.9	54.3	NS	45.6	37.2	NS
Lee et al[7]	86.9	98	NS	81.8	80.6	NS	76	76.1	NS	78.8	69.2	NS	51	55.9	NS	45.3	55.9	NS
Ahn et al[8]							80.1	85.7	NS							67.8	54.8	NS
Memeo et al[9]	88	63	NS				59	44	NS	80	60	NS				19	23	NS
Lee et al[10]	95.3	93.9	NS	89.7	89.5	NS	89.7	87.3	NS	60.5	81.5	NS	60.3	66.7	NS	60.3	58.6	NS
Yoon et al[11]	95	98	NS	86	84	NS				82	88	NS	63	62	NS
Xiao et al[12]	95.1	89.5	NS	78	76.7	NS				87.8	82.6	NS	70.7	68.6	NS
Sposito et al[13]				75	79	NS	38	46	NS				41	44	NS	25	11	NS
Cheung et al[14]	100	93	NS	85.6	84.1	NS	69.1	77.6	NS	95	69.2	NS	72.8	61.5	NS	51.8	61.5	NS
Ryu et al[15]	89.9	89.9	NS	84.7	68	NS	70.9	63.1	NS	79.5	72.4	NS	58	56.1	NS	42.5	50.4	NS
Rhu et al[16]	96.8	96.8	NS	94.5	94.5	NS	94.5	94.5	NS	77.8	77.8	NS	68.3	68.3	NS	62.5	62.5	NS
Guro et al[17]							77.3	60.2	NS							50.8	40.1	NS
El-Gendi et al[18]										88	84	NS	58.7	54	NS
Inoue et al[19]	97.8	87.9	NS	78.8	70.6	NS				83.8	75	NS	57.5	54.8	NS
Kim et al[20]				93.9	93.8								79.6	91.1	NS
Deng et al[21]	96.2	96.8	NS	72.6	73.4	NS	45.3	46.9	NS	90.5	91.7	NS	53.7	54.4	NS	24.6	19.9	NS
Wu et al[22]	93	81.4	NS	81.4	75.5	NS	69.8	62.8	NS	75.6	69.8	NS	60.5	53.5	NS	44.2	38.4	NS
Tsai et al[23]	90.3	85	0.002	82.9	63.6	0.002	78.1	57.6	0.002	72.9	60.8	NS	49.2	43	NS	37.9	31	NS
Di Sandro et al[24]				68	76								44	44	NS
Li et al[25]	96.3	95.3	NS	68.4	90.5	NS				84	87.2	NS	36	59.7	NS
Kim et al[26]	94.4	100	NS	94.4	92.9	NS				93.8	76.5	NS	56.3	41.3	NS
Chen et al[27]				69.8	74	NS							51.6	57.8	NS
Untereiner et al[28]				78	79	NS							72	58.6	NS
Yoon et al[29]	98.1	93.8	NS	87	90.8	NS	78.6	84.3	NS	81	85.3	NS	62	64.7	NS	49.1	56.2	NS
Peng et al[30]	95.8	92.8		77	77	NS				71.9	79.1	NS	51.4	46.2	NS
Yamamoto et al[31]				82	78.4	NS	58.9	62.3	NS				52.6	40.3	NS	24	24.1	NS
Lee et al[32]	96.6	92.8	NS	73.3	93.1	NS	88.8	76.1	NS	84.4	64	NS	60.2	93.1	NS	67.4	63.9	NS
Navarro et al[33]							90	90	NS							58	40	NS
Delvecchio et al[34]	100	95	NS	100	88	NS	77	75	NS	67	79	NS	44	54	NS	29	46	NS
Ho et al[35]	95.6	87.5	0.036	84.9	70.3	0.036	84.9	61.1	0.036	80.0	73.3	NS	40.0	41.1	NS	20.0	22.2	NS

DFS: Disease-free survival; LLR: Laparoscopic liver resection; NS: Statistically not significant; OLR: Open liver resection; OS: Overall survival.