Long-term survival outcome of laparoscopic liver resection for hepatocellular carcinoma

Table 2 Summary of comparative studies: Baseline clinical-pathological features of both treatment groups

Ref.	Difference between study groups	ICG, %		Child A/B/C, %		Tumor size in cm				Microvascular invasion, %
		LLR	OLR	LLR	OLR	LLR	+/- SD/95%CI	OLR	+/- SD/95%CI	LLR	OLR
Belli et al[5]	Tumor size, AFP level, margin width			91/9/0	93.6/6.4/0	3.8	+/-1.3	6	+/-2.3	37	39.2
Tranchart et al[6]						3.6	+/-1.75	3.7	+/-2.1	33.3	35.7
Lee et al[7]	Cirrhosis, previous abdominal surgery, margin width					2.5	1.5-9	2.9	1.2-9
Ahn et al[8]		14.5	13.1			2.6	+/-1.5	2.8	+/-1.2	15.7	19.6
Memeo et al[9]	Margin width			98/2/0	96/4/0	3.2	0.9-11	3.7	0.1-15
Lee et al[10]	Margin width			97.6/2.4/0	97.6/2.4/0	5.4	2-16	4.4	2-14	52.5	43.5
Yoon et al[11]	Margin width	12.1	12.4			2.87	0.7-4.9	3.04	0.2-4.9
Xiao et al[12]				95/5/0	96.5/3.5/0	4.22	+/-2.05	4.3	+/-1.49
Sposito et al[13]		15	15	98/2/0	95/5/0	2.6	1-6.5	2.2	1-8.5	56	37
Cheung et al[14]	Age			100/0/0	96.6/3.4/0	3	1.2-5	3.5	1.5-8.5
Ryu et al[15]		11.9	14			3.9	1.1-17	4.9	1-14.5	30	40
Rhu et al[16]				37.7/0/0	37.1/0/0	3.1	+/-5.7	3.1	+/-1.7	56.6	58.8
Guro et al[17]	Cirrhosis, tumor size			95/2.4/2.4	88/9.9/7.2	4.1	+/-2.4	6.3	+/-3.8
El-Gendi et al[18]				100/0/0	100/0/0	3.3	+/-0.57	3.4	0.59	60	68
Inoue et al[19]				89/11/0	100/0/0	2.5		2.6		12	13
Kim et al[20]		9.3	8			2.8		2.8		25	23
Deng et al[21]	Procedure type			100/0/0	100/0/0	2.5		2.8		10.2	16.6
Wu et al[22]						3.5	0.9-12.5	3.5	0.8-11.3	38.4	41.9
Tsai et al[23]	Procedure magnitude, tumor size			93/7/0	98/2/0	3.9	+/-2.6	7.2	+/-5.3
Di Sandro et al[24]				87/13/0	84/16/0	2.5	2-3.0	2.5	1.8-3.3	29.3	29.3
Li et al[25]	Tumor size					4	+/-2	5.7	+/-3	17	30
Kim et al[26]		10.4	12.8			3	+/-2.1	3.2	+/-3.14	22.2	27.8
Chen et al[27]		6.9	6.9			7.3	+/-3.4	7.6	+/-4.2	37	32
Untereiner et al[28]				64/0/0	73/0/0	3	2.1-4.9	3	2.3-5
Yoon et al[29]	ASA class, medical disease	13.6	14	66.8/0/0	65.4/0/0	2.83	1.28	2.9	1.31	14.3	15.7
Peng et al[30]				94/6/0	91/9/0	4.8	2-8.5	5.5	2-8.5	30	30
Yamamoto et al[31]				88/22/0	84/16/0	1.7	1.2-4.2	2	0.7-9.9
Lee et al[32]				90/10/0	91/9/0	2.5	7-14.5	2.6	1.1-14.5	8.6	8.6
Navarro et al[33]						3.5	8.5	3.3	8.1	51.2	51.2
Delvecchio et al[34]				97/3/0	98/2/0	4	3.0-16	7	1.5-14
Ho et al[35]	Hepatitis C carrier status margin width			100/0/0	92/8/0	3.5	2-5	4	3-5	28.9	30

AFP: Alpha-fetoprotein; ASA: American Society of Anesthesiologists; CI: Confidence interval; ICG: Indocyanine green retention at 15 min; LLR: Laparoscopic liver resection; OLR: Open liver resection; SD: Standard deviation.