Evolution and current status of the subclassification of intermediate hepatocellular carcinoma

doi:10.4240/wjgs.v12.i3.85

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World Journal of Gastrointestinal Surgery

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1948-9366

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Surg. Mar 27, 2020; 12(3): 85-92
Published online Mar 27, 2020. doi: 10.4240/wjgs.v12.i3.85

Table 1 Bolondi criteria

BCLC sub-stage	B1	B2	B3	B4
CPT score	5-7	5-6	7	8-9¹
Beyond Milan and within Ut-7	In	Out	Out	Any
ECOG (tumor related) PS	0	0	0	0-1
PVT	No	No	No	No
1^st option	TACE	TACE or TARE		BSC
Alternative	LT TACE + ablation	SOR	Research trials TACE SOR	LT²

¹With severe/refractory ascites and/or jaundice.

²Only if Up-to-7 IN and PS0. CPT: Child Pugh score; BSC: Best supportive care; LT: Liver transplantation; SOR: Sorafenib; TACE: Transcatheter arterial chemoembolization; TARE: Transarterial radioembolization; PVT: Portal vein thrombosis; Ut-7: Up to-7 criteria.

Citation: Yi PS, Wang H, Li JS. Evolution and current status of the subclassification of intermediate hepatocellular carcinoma. World J Gastrointest Surg 2020; 12(3): 85-92
URL: https://www.wjgnet.com/1948-9366/full/v12/i3/85.htm
DOI: https://dx.doi.org/10.4240/wjgs.v12.i3.85