Retrospective cohort study of statin therapy effect on resected colorectal liver metastases

Table 3 Effect of statins on patient and tumour variables

Demographic, clinical and pathological factors	Statin therapy use (n = 181)	No statin therapy use (n = 408)	P value
Age > 65 yr	106	236	0.947
Male gender	119	270	0.827
Synchronous presentation	67	158	0.646
Neutrophil-to-lymphocyte ratio ≥ 5	22	74	0.065
Platelet-to-lymphocyte ratio ≥ 150	88	211	0.436
Neo-adjuvant chemotherapy	38	87	0.894
Hemi-hepatectomy or more	61	157	0.241
Largest tumour size ≥ 5 cm	53	127	0.615
Solitary hepatic metastases	91	203	0.973
Steatosis - None	127	299	0.634
Lymphatic invasion	16	50	0.215
Perineural invasion	13	20	0.276
Vascular invasion	88	176	0.246
Biliary invasion	62	119	0.238
Resection margin R0	133	294	0.823