Hepatocellular carcinoma – time to take the ticket

Table 2 Extended criteria currently in use

Extended criteria
UCSF[28]	Single tumor ≤ 6.5 cm in diameter or no more than 3 lesions ≤ 4.5 cm in diameter, and total tumor diameter ≤ 8 cm
Asan criteria[29]	≤ 6 tumors, all ≤ 5 cm in diameter, and no gross vascular invasion
Valencia criteria[30]	1-3 tumors ≤ 5 cm and cumulative tumor burden ≤ 10 cm
Up-to-7 criteria[14]	Sum of the sizes of the largest tumor (in cm) and the number of tumors ≤ 7
CUN criteria[31]	Single tumor ≤ 6 cm or up to 3 nodules ≤ 5 cm
Mount-Sinai[32]	Any number of lesions, each is 5-7 cm in diameter
Edmonton[33]	Number of single tumors ≤ 7, tumor ≤ 5 cm in diameter
Dallas[34]	Single tumor diameter ≤ 6 cm or 2-4 tumors each ≤ 5 cm in diameter
Tokyo[35]	≤ 5 tumors not exceeding 5 cm in diameter
Shanghai[36]	Single tumor ≤ 9 cm in diameter or no more than 3 nodules with the largest nodule ≤ 5 cm in diameter, overall tumor diameter ≤ 9 cm without extrahepatic metastasis, lymph node or macrovascular invasion