Prediction of overall survival following colorectal cancer surgery in elderly patients

Table 5 Comparison between Singapore General Hospital; and Kyungpook National University Chilgok Hospital cohorts

Variable	SGH(n = 1267)		KNUCH(n = 910)
	n		n
Age, median (range), yr	1267	77 (70-102)	910	75 (70-96)
Gender
Male	658	(51.9)	496	(54.5)
Female	609	(48.1)	414	(45.5)
Lesion sites
Colon	790	(62.3)	540	(59.3)
Rectum	477	(37.6)	370	(40.7)
Tumor grade
Well differentiated	117	(9.0)	29	(3.2)
Moderately differentiated	1009	(79.6)	809	(88.9)
Poorly differentiated	70	(5.5)	29	(3.2)
Mucinous/signet ring cell	71	(5.6)	43	(4.7)
Laboratory parameters, mean (SD)
Creatinine, µmol/L	1267	88.9 (54.9)	910	83.8 (38.6)
Urea, mmol/L	1267	5.5 (2.7)	910	2.7 (1.1)
Hemoglobin, g/dL	1267	11.8 (1.8)	910	12.0 (2.1)
WBC count, × 109/L	1267	7.9 (2.6)	908	8.0 (18.2)
Platelet count, × 109/L	1267	300.6 (104.6)	910	287.1 (95.3)
Serum albumin, g/L	1119	33.7 (5.5)	910	39.9 (4.6)
CEA, median (IQR), µg/L	1196	4.3 (2.6–14.2)	887	2.4 (1.5–4.8)
Comorbidities
Diabetes	331	(26.1)	167	(18.4)
Hypertension	416	(32.8)	415	(45.6)
Ischemic heart disease	47	(3.7)	14	(1.5)
Congestive heart failure	41	(3.2)	20	(2.2)
PVD	30	(2.4)	0	(0.0)
COPD	61	(4.8)	66	(7.3)
Previous stroke	90	(7.1)	50	(5.5)
End stage renal disease	26	(2.1)	6	(0.7)
ASA
1	178	(14.0)	152	(16.7)
2	857	(67.6)	724	(79.6)
3	225	(17.8)	34	(3.7)
4	7	(0.6)	0	(0.0)
T stagea
Tis	2	(0.2)	8	(0.9)
T1	95	(7.5)	72	(7.9)
T2	188	(14.8)	134	(14.7)
T3	752	(59.4)	587	(64.5)
T4a	97	(7.7)	76	(8.4)
T4b	133	(10.5)	29	(3.2)
ypCR	0	(0.0)	4	(0.4)
N stagea
N0	688	(54.3)	577	(63.4)
N1a	148	(11.7)	124	(13.6)
N1b	185	(14.6)	109	(12.0)
N1c	4	(0.3)	1	(0.1)
N2a	99	(7.8)	58	(6.4)
N2b	143	(11.3)	41	(4.5)
Short term outcomes
Anastomotic leak	16	(1.3)	44	(4.8)
30-d morbidity	297	(23.4)	212	(23.3)
30-d mortality	30	(2.4)	1	(0.001)

^aAmerican Joint Committee on Cancer Staging, 7^th edition. All values are reported as n (%) unless otherwise stated. KNUCH: Kyungpook National University Chilgok Hospital; SGH: Singapore General Hospital; WBC: White blood cell; CEA: Carcinoembryonic antigen; PVD: Peripheral vascular disease; COPD: Chronic obstructive pulmonary disease; ASA: American Society of Anesthesiologists; ypCR: Pathological complete response following neoadjuvant therapy.