Prediction of overall survival following colorectal cancer surgery in elderly patients

Table 4 Multivariable model predicting all-cause mortality, truncated at 3 years from time of surgery

Variable	Hazard ratio	2.5thpercentile	97.5thpercentile	P value
Serum albumin < 35 g/dL	1.41	1.08	1.83	0.011
CEA ≥ 20 µg/L	2.51	1.92	3.28	< 0.001
T stage
T1/Tis	1.00 (ref)	-	-	-
T2	1.11	0.23	5.41	0.894
T3	6.18	1.55	24.6	0.010
T4	17.9	4.45	72.1	< 0.001
Tumor grade
Well differentiated	1.00 (ref)	-	-	-
Moderately differentiated	2.24	1.04	4.82	0.040
Poorly differentiated or mucinous	3.54	1.54	8.15	0.003
Rectal lesion	1.47	1.11	1.96	0.007
Chronic obstructive lung disease	1.87	1.11	3.17	0.019

These factors were identified following progressive elimination of non-significant candidate predictors until all predictors retained in the final model had P values below 0.05. CEA: Carcinoembryonic antigen; ref: Reference.