Autologous bone marrow derived stem cell therapy in patients with type 2 diabetes mellitus - defining adequate administration methods

Table 12 Comparison of different case arms (Group I, II and III) with control arm (Group IV) at 6 mo

Parameter	Group I	Group II	Group III	Group IV	P value Group I	P value Group II	P value Group III
Insulin requirement	21 ± 7	22 ± 5	34 ± 11	33 ± 5	0.174	0.183	0.69
HbA1c	6.5 ± 0.16	6.7 ± 0.12	6.7 ± 0.21	6.6 ± 0.22	0.816	0.704	0.779
HOMA IR%	6.96 ± 1.32	4.76 ± 0.45	6.13 ± 1.5	4.9 ± 1.2	0.404	0.358	0.322
HOMA B%	63.33 ± 13.99	46.86 ± 2.62	59.58 ± 22.96	91.7 ± 14.6	0.096	0.29	0.213
Fasting C-peptide (ng/mL)	2.94 ± 0.80	1.896 ± 0.29	2.49 ± 0.74	1.5 ± 0.4	0.091	0.34	0.187
Stimulated C-peptide (ng/mL)	4.23 ± 0.84	3.008 ± 0.26	3.48 ± 0.87	2.8 ± 0.	0.14	0.566	0.412

HbA1c: Glycosylated hemoglobin; HOMA-IR: Homeostasis model assessment insulin resistance index; HOMA-B: Homeostasis model assessment beta cell function.