Autologous bone marrow derived stem cell therapy in patients with type 2 diabetes mellitus - defining adequate administration methods

Table 11 Comparison of different case arms (Group I, II and III) with control arm (Group IV) at zero month

Parameter	Group I	Group II	Group III	Group IV	P value Group I	P value Group II	P value Group III
Insulin requirement	44 ± 5	40 ± 4	45 ± 7	44 ± 5	0.979	0.541	0.927
HbA1c	6.8 ± 0.18	6.4 ± 0.16	6.7 ± 0.15	6.6 ± 0.24	0.983	0.453	0.9
HOMA IR%	11.72 ± 5.39	3.31 ± 1.11	5.92 ± 0.67	4.6 ± 1.5	0.544	0.327	0.333
HOMA-B%	146.2 ± 56.44	40.75 ± 12.02	129.57 ± 65.20	77.8 ± 22.4	0.593	0.212	0.559
Fasting C-peptide (ng/mL)	2.97 ± 1.51	1.282 ± 0.14	1.415 ± 0.25	1.1 ± 0.20	0.174	0.087	0.139
Stimulated C-peptide (ng/mL)	4.26 ± 1.59	2.63 ± 0.23	2.37 ± 0.36	2.1 ± 0.3	0.144	0.132	0.324

HbA1c: Glycosylated hemoglobin; HOMA-IR: Homeostasis model assessment insulin resistance index; HOMA-B: Homeostasis model assessment beta cell function.