Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients

doi:10.4239/wjd.v8.i3.112

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 8, Issue 3

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (9640)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-6) series.

Item

Count

PDF

509

WORD

402

HTML

3632

Tables (1-6)

161

Sum=4704

Featured Article

The chart showing Browse series, Download series.

Item

Count

Browse

779

Download

1783

Sum=2562

Publishing Process of This Article

Item

Count

Browse

919

Download

1452

Sum=2371

Mar 15, 2017 (publication date) through Apr 24, 2024

Times Cited of This Article

Times Cited (7)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Prospective Study

World J Diabetes. Mar 15, 2017; 8(3): 112-119
Published online Mar 15, 2017. doi: 10.4239/wjd.v8.i3.112

Table 6 Genotypic distribution of responders and non-responders having micro-/ macro-albuminuria

Gene	Genotype (n = 252)	Micro-albuminuric group (n = 170)			Macro-albuminuric group (n = 82)
		R (%) (n = 76)	NR (%) (n = 94)	P-value¹	Rc (%) (n = 45)	NR (%) (n = 37)	P-value²
ACE (I/D)	II	23 (45)	28 (55)	0.974	15 (56)	12 (44)	0.636
	ID	42 (44)	53 (56)		20 (53)	18 (47)
	DD	11 (49)	13 (54)		10 (59)	7 (41)
AGT (M235T)	MM	25 (60)	17 (40)	0.11	9 (47)	10 (53)	0.201
	MT	36 (40)	53 (60)		23 (51)	22 (49)
	TT	15 (38)	24 (62)		13 (72)	5 (28)

¹P > 0.05: Comparison between responders and non-responders to therapy in micro-albuminuric group;

²P > 0.05: Comparison between responders and non-responders to therapy in macro-albuminuric group. ACE: Angiotensin converting enzyme; AGT: Angiotensinogen; R: Responders; NR: Non-responders.

Citation: Aggarwal N, Kare PK, Varshney P, Kalra OP, Madhu SV, Banerjee BD, Yadav A, Raizada A, Tripathi AK. Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients. World J Diabetes 2017; 8(3): 112-119
URL: https://www.wjgnet.com/1948-9358/full/v8/i3/112.htm
DOI: https://dx.doi.org/10.4239/wjd.v8.i3.112