©The Author(s) 2016.
World J Diabetes. May 10, 2016; 7(9): 189-197
Published online May 10, 2016. doi: 10.4239/wjd.v7.i9.189
Published online May 10, 2016. doi: 10.4239/wjd.v7.i9.189
Table 1 Physiological actions of amylin
| Neuroendocrine effects |
| Inhibiting insulin secretion in a high concentration |
| Inhibiting glucagon secretion at mealtime |
| Delaying nutrient delivery from stomach to the small intestine |
| Reducing food intake by a signal from the central nervous system |
| Metabolic effects |
| Co-regulating glucose with insulin and glucagon |
| Inhibiting muscle glycogen synthesis[15] |
| Stimulating oxidative responses and low density lipoprotein uptake in insulin-producing cells |
| Inhibiting bone resorption |
| Lipolytic-like effects |
| Renal effects |
| Renin ↑ |
| Angiotensin II ↑ |
| Regulating renal growth |
| Regulating water-sodium homeostasis |
| Haemodynamic effect |
| Aldosterone ↑ |
| Hypocalcaemia |
| Vasodilation |
- Citation: Zhang XX, Pan YH, Huang YM, Zhao HL. Neuroendocrine hormone amylin in diabetes. World J Diabetes 2016; 7(9): 189-197
- URL: https://www.wjgnet.com/1948-9358/full/v7/i9/189.htm
- DOI: https://dx.doi.org/10.4239/wjd.v7.i9.189