Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants

Table 5 Effect of the extract from the different extraction methods on blood glucose in streptozotocin-induced diabetic rats

Group	Before induction	7 d after induction	Days after treatment
			7th	14th	21st
CME	79.4 ± 4.5	344.6 ± 10.3	282.8 ± 17.6	195.8 ± 18.3	106.5 ± 6.7
SEE	85.3 ± 3.2	396.8 ± 15.7	342.5 ± 14.7	264.9 ± 16.8	121.1 ± 10.2
MAE	82.7 ± 5.1	373.3 ± 13.6	331.3 ± 11.4	237.1 ± 8.9	102.4 ± 7.6
PC	91.6 ± 4.5	389.4 ± 11.9	359.0 ± 12.6	266.3 ± 13.2	97.3 ± 5.8
NC	80.6 ± 3.8	365.5 ± 9.8	395.1 ± 16.3	419.6 ± 10.2	448.4 ± 17.4
HC	83.2 ± 6.2	84.8 ± 4.7	83.9 ± 7.8	84.7 ± 6.5	84.2 ± 7.1

Values are mean ± SD (mg/dL) of readings from 6 rats per group. CME: Cold maceration extract; SEE: Soxhlet extraction extract; MAE: Microwave-assisted extraction extract; PC: Positive control; NC: Negative control; HC: Healthy control.