Interplay between Rab27a effectors in pancreatic &beta;-cells

doi:10.4239/wjd.v6.i3.508

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Apr 15, 2015; 6(3): 508-516
Published online Apr 15, 2015. doi: 10.4239/wjd.v6.i3.508

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Figure 4 Schematic model of GDP-bound Rab27a function in pancreatic β-cells. Endocytosis is a complex process that involves cargo sorting, membrane invagination, vesicle scission and vesicle targeting. GDP-bound Rab27a modulates F-actin assembly and regulates the retrograde transport of the internalized secretory membrane, at the stage after scission from the plasma membrane. Scission is indicated by the dynamin step.

Citation: Yamaoka M, Ishizaki T, Kimura T. Interplay between Rab27a effectors in pancreatic β-cells. World J Diabetes 2015; 6(3): 508-516
URL: https://www.wjgnet.com/1948-9358/full/v6/i3/508.htm
DOI: https://dx.doi.org/10.4239/wjd.v6.i3.508

Yamaoka M, Ishizaki T, Kimura T. Interplay between Rab27a effectors in pancreatic β-cells. World J Diabetes 2015; 6(3): 508-516 [PMID: 25897360 DOI: 10.4239/wjd.v6.i3.508]

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