Simvastatin, atorvastatin, and pravastatin equally improve the hemodynamic status of diabetic rats

Figure 1 Effects of four weeks treatment with atorvastatin, simvastatin, and pravastain (10 mg/kg per day) on diabetic rats and control. A: Stroke volume (mL); B: Ejection fraction (%); C: Cardiac output index (mL/min x 100 g BW). The results represent the mean ± SEM of 8 animals per group. All the statins significantly improved these CV parameters in diabetic rats. ^aP < 0.05 for diabetic rats vs CT; ^cP < 0.05 for untreated diabetic rats vs treated diabetic rats. STZ: Streptozotocin; AV: Atorvastatin; SV: Simvastatin; PV: Pravastatin; CT: Control.