Recent advances in the molecular genetics of type 2 diabetes mellitus

doi:10.4239/wjd.v5.i2.128

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Apr 15, 2014; 5(2): 128-140
Published online Apr 15, 2014. doi: 10.4239/wjd.v5.i2.128

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Figure 4 Model for the role of High Mobility Group A1 in type 2 diabetes mellitus. As a transcriptional regulator of the INSR gene, HMGA1 gene variants may lead to decreased INSR gene transcription. This loss of insulin receptor (INSR) underlies the resultant insulin resistance and T2D in affected individuals. T2D: Type 2 diabetes.

Citation: Brunetti A, Chiefari E, Foti D. Recent advances in the molecular genetics of type 2 diabetes mellitus. World J Diabetes 2014; 5(2): 128-140
URL: https://www.wjgnet.com/1948-9358/full/v5/i2/128.htm
DOI: https://dx.doi.org/10.4239/wjd.v5.i2.128