Effect of treatment of overt hypothyroidism on insulin resistance

Table 3 Comparison between different variables before and after thyroxine replacement

Variable	Before treatment (mean ± SD)	After treatment(mean ± SD)	P-value
BMI	31.1 ± 6.8	31.4 ± 7.2	0.485
TSH	22.4 ± 36.2	3.0 ± 1.9	0.010
FT4	11.2 ± 4.0	14.5 ± 2.6	0.001
FT3	4.4 ± 1.0	4.7 ± 0.7	0.037
FPG	93.5 ± 14.7	90.2 ± 12.2	0.216
FI	10.6 ± 8.1	13.6 ± 7.3	0.047
IR	2.5 ± 2.1	3.0 ± 1.9	0.204
TG	144.8 ± 85.4	128.1 ± 64.8	0.175

BMI: Body mass index; TSH: Thyrotropin; FPG: Fasting plasma glucose; FI: Fasting insulin; IR: Insulin resistance; FT4: Free tetraiodothyronine; FT3: Free triiodothyronine; TG: Triglycerides; TCH: total cholesterol.