Cardiometabolic health among gastric bypass surgery patients with polycystic ovarian syndrome

Table 1 Mean body mass index and cardiometabolic disease risk factor values among women with polycystic ovary syndrome before and 1 year after gastric bypass surgery by ethnic group

		Pre-surgery	1-yr follow up
	n4	Estimate (95%CI)	Estimate (95%CI)
Hispanic (n = 257)1
BMI (kg/m2)	257	45.5 (44.7-46.4)	35.5 (34.6-36.3)
Weight (kg)	257	118.4 (115.8-120.9)	92.3 (89.8-94.7)
EWL (%)	257		54.5 (1.9)
Percent weight loss (%)	257		22.0 (0.6)
Total cholesterol (mg/dL)	28	198.1 (190.4-205.8)	160.2 (154.0-166.4)
HDL cholesterol (mg/dL)	28	49.5 (46.8-52.1)	48.7 (46.4-51.0)
LDL cholesterol (mg/dL)	24	120.9 (112.9-128.9)	91.0 (86.0-95.9)
Triglycerides (mg/dL)	28	148.6 (128.7-168.6)	104.8 (93.9-115.8)
Hemoglobin A1c (%)	58	6.2 (6.0-6.3)	5.6 (5.5-5.6)
ALT (U/L)	99	28.1 (25.8-30.4)	23.0 (20.7-25.4)
AST (U/L)	100	23.5 (22.0-25.0)	21.6 (19.8-23.4)
Non-Hispanic black (n = 97)2
BMI (kg/m2)	97	46.8 (45.5-48.2)	37.7 (36.2-39.2)
Weight (kg)	97	128.2 (123.5-132.8)	103.1 (98.5-107.8)
EWL (%)	97		47.5 (3.1)
Percent weight loss (%)	97		19.5 (1.0)
Total cholesterol (mg/dL)	6	184.5 (166.6-202.3)	154.7 (140.2-169.2)
HDL cholesterol (mg/dL)	6	50.6 (45.0-56.1)	53.0 (47.4-58.6)
LDL cholesterol (mg/dL)	6	111.7 (97.0-126.5)	88.9 (76.4-101.3)
Triglycerides (mg/dL)	6	99.7 (80.0-119.5)	70.0 (56.8-83.3)
Hemoglobin A1c (%)	15	6.4 (5.9-6.8)	5.8 (5.3-6.3)
ALT (U/L)	23	18.6 (16.3-20.9)	16.0 (12.6-19.4)
AST (U/L)	23	19.2 (17.4-20.9)	18.6 (16.4-20.7)
Non-Hispanic white (n = 35)3
BMI (kg/m2)	35	45.7 (43.2-48.1)	36.7 (34.4-39.0)
Weight (kg)	35	123.9 (116.5-131.2)	99.58 (92.3-106.9)
EWL (%)	35		50.2 (5.2)
Percent weight loss (%)	35		20.2 (1.7)
Total cholesterol (mg/dL)	7	200.9 (178.1-223.7)	172.8 (160.5-185.2)
HDL cholesterol (mg/dL)	7	49.7 (44.3-55.1)	49.6 (43.8-55.4)
LDL cholesterol (mg/dL)	6	124.2 (104.2-144.2)	96.6 (80.4-112.9)
Triglycerides (mg/dL)	7	160.5 (120.9-200.1)	137.8 (104.9-170.7)
Hemoglobin A1c (%)	5	6.3 (5.8-6.8)	5.9 (5.0-6.8)
ALT (U/L)	10	30.0 (23.7-36.0)	22.0 (16.6-27.4)
AST (U/L)	10	23.7 (19.7-27.8)	20.8 (16.6-25.0)

¹Differences were statistically significant (P < 0.001), except for high-density lipoprotein (HDL) cholesterol and aspartate aminotransferase (AST);

²All differences were statistically significant (P < 0.05), except for HDL cholesterol, hemoglobin A1c (HbA1c), alanine aminotransferase (ALT) and AST were not significant;

³All differences were statistically significant (P < 0.05) except for HDL cholesterol, triglycerides, HbA1c, ALT and AST; ⁴Number of patients with data at baseline and 1 year follow up. BMI: Body mass index; EWL: Estimated weight loss; LDL: Low-density lipoprotein.