Expression and clinical value of the plasma peroxiredoxin family in early pregnancy for predicting subsequent gestational diabetes mellitus

doi:10.4239/wjd.123635

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Aug 15, 2026; 17(8): 123635
Published online Aug 15, 2026. doi: 10.4239/wjd.123635

Table 5 Diagnostic value of plasma peroxiredoxin family members in women with early gestational diabetes mellitus

Indicators	AUC	P value	Sensitivity	Specificity	Youden index	Cutoff	95%CI
PRDX1	0.757	0.000	0.874	0.550	0.423	52.80	0.713-0.802
PRDX2	0.620	0.000	0.644	0.581	0.225	63.15	0.567-0.672
PRDX3	0.626	0.000	0.365	0.833	0.198	199.66	0.574-0.677
PRDX4	0.776	0.000	0.644	0.788	0.432	123.10	0.733-0.820
PRDX5	0.742	0.000	0.946	0.514	0.459	65.51	0.695-0.789
PRDX6	0.589	0.001	0.392	0.775	0.167	527.38	0.536-0.642
Combined	0.836	0.000	0.851	0.703	0.554		0.799-0.873

Combined: Indicates the joint receiver operating characteristic analysis of peroxiredoxin 1, peroxiredoxin 4 and peroxiredoxin 5.

PRDX: Peroxiredoxin; AUC: Area under the curve; CI: Confidence interval.

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Citation: Xu XP, Ding S, Che YM, Li J, Zhang Z, Qian C. Expression and clinical value of the plasma peroxiredoxin family in early pregnancy for predicting subsequent gestational diabetes mellitus. World J Diabetes 2026; 17(8): 123635
URL: https://www.wjgnet.com/1948-9358/full/v17/i8/123635.htm
DOI: https://dx.doi.org/10.4239/wjd.123635

Xu XP, Ding S, Che YM, Li J, Zhang Z, Qian C. Expression and clinical value of the plasma peroxiredoxin family in early pregnancy for predicting subsequent gestational diabetes mellitus. World J Diabetes 2026; 17(8): 123635 [DOI: 10.4239/wjd.123635]

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