Clinical significance of bone metabolic markers in osteoporosis-complicated type 2 diabetes mellitus and risk determinants: A retrospective study

doi:10.4239/wjd.123389

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World Journal of Diabetes

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1948-9358

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Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Aug 15, 2026; 17(8): 123389
Published online Aug 15, 2026. doi: 10.4239/wjd.123389

Table 3 Intergroup comparison of bone metabolic markers, mean ± SD/median (interquartile 1, interquartile 3)

	OP group (n = 134)	Non-OP group (n = 81)	t/U	P value
ALP	70.00 ± 11.25	81.43 ± 54.54	1.145	0.254
PTH	72.89 (45.17, 103.54)	42.36 (26.25, 54.62)	4.262	< 0.0001
β-CTX	0.45 (0.23, 0.96)	0.37 (0.22, 0.54)	2.584	0.010
PINP	44.18 (30.52, 68.69)	42.77 (32.12, 68.52)	0.363	0.717
Ca	2.26 ± 0.19	2.22 ± 0.16	1.560	0.120
P	1.26 ± 0.10	1.18 ± 0.51	1.389	0.166

OP: Osteoporosis; ALP: Alkaline phosphatase; PTH: Parathyroid hormone; β-CTX: Β-C-terminal cross-linked peptide of type I collagen; PINP: Propeptide of type I procollagen; Ca: Calcium; P: Phosphorus.

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Citation: Lu HL, Yu F, Zhou HF, Hu P, Gan SL. Clinical significance of bone metabolic markers in osteoporosis-complicated type 2 diabetes mellitus and risk determinants: A retrospective study. World J Diabetes 2026; 17(8): 123389
URL: https://www.wjgnet.com/1948-9358/full/v17/i8/123389.htm
DOI: https://dx.doi.org/10.4239/wjd.123389

Lu HL, Yu F, Zhou HF, Hu P, Gan SL. Clinical significance of bone metabolic markers in osteoporosis-complicated type 2 diabetes mellitus and risk determinants: A retrospective study. World J Diabetes 2026; 17(8): 123389 [DOI: 10.4239/wjd.123389]

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