Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes

doi:10.4239/wjd.121422

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World Journal of Diabetes

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1948-9358

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Aug 15, 2026; 17(8): 121422
Published online Aug 15, 2026. doi: 10.4239/wjd.121422

Table 5 Multivariate linear regression analysis of type 2 diabetes mellitus with bone mineral density, epicardial adipose tissue volume, and epicardial adipose tissue density

Model	BMD		EAT volume		EAT density
Model	β (95%CI)	P value	β (95%CI)	P value	β (95%CI)	P value
Model 1	-9.579 (-11.617 to -7.542)	< 0.001	24.122 (19.546-28.697)	< 0.001	2.255 (1.711-2.799)	< 0.001
Model 2	1.411 (-0.411 to 3.233)	0.129	4.304 (-0.070 to 8.679)	0.054	3.611 (3.055-4.167)	< 0.001
Model 3	0.506 (-1.477 to 2.489)	0.617	-3.363 (-8.056 to 1.331)	0.16	4.131 (3.528-4.733)	< 0.001

Model 1: Unadjusted. Model 2: Adjusted for age and sex. Model 3: Further adjusted for smoking status, alcohol consumption, hypertension, dyslipidemia, and body mass index. BMD: Bone mineral density; EAT: Epicardial adipose tissue.

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Citation: Liu YK, Wu FY, Jiang CP, Xia YX, Li Y, Zeng WW, Zhang SY, Fan DN, Zhang MX, Liu TC, Wu XP, Dong Y, Chen W, Zhao YH, Li T, Li Z, Xu XY. Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes. World J Diabetes 2026; 17(8): 121422
URL: https://www.wjgnet.com/1948-9358/full/v17/i8/121422.htm
DOI: https://dx.doi.org/10.4239/wjd.121422

Liu YK, Wu FY, Jiang CP, Xia YX, Li Y, Zeng WW, Zhang SY, Fan DN, Zhang MX, Liu TC, Wu XP, Dong Y, Chen W, Zhao YH, Li T, Li Z, Xu XY. Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes. World J Diabetes 2026; 17(8): 121422 [DOI: 10.4239/wjd.121422]

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