Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes

doi:10.4239/wjd.121422

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 8

This Article

(16)

(13)

(0)

(130)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Aug 15, 2026; 17(8): 121422
Published online Aug 15, 2026. doi: 10.4239/wjd.121422

Table 3 Comparison between non-type 2 diabetes mellitus patients and type 2 diabetes mellitus patients with different durations after matching, n (%)/median (interquartile range)

Variables	Non-T2DM vs short-duration T2DM		P value	Non-T2DM vs intermediate-duration T2DM		P value	Non-T2DM vs long-duration T2DM		P value
Variables	Non-T2DM	Short-duration T2DM	P value	Non-T2DM	Intermediate-duration T2DM	P value	Non-T2DM	Long-duration T2DM	P value
n	355	355		308	308		664	664
Age (years)	57.00 (50.00, 64.00)	57.00 (49.00, 64.00)	0.937	59.00 (51.75, 66.00)	59.00 (52.00, 67.00)	0.746	59.00 (54.00, 67.00)	60.00 (54.00, 68.00)	0.133
BMI (kg/m²)	24.02 (21.64, 26.13)	24.09 (21.60, 26.26)	0.874	24.22 (22.35, 26.45)	24.32 (22.03, 26.68)	0.878	24.12 (22.20, 26.23)	23.88 (21.88, 26.18)	0.218
Male sex	203 (57.18)	223 (62.82)	0.125	221 (71.75)	211 (68.51)	0.379	457 (68.83)	447 (67.32)	0.556
Smoke	75 (21.13)	84 (23.66)	0.418	84 (27.27)	71 (23.05)	0.227	137 (20.63)	133 (20.03)	0.785
Alcohol	37 (10.42)	38 (10.70)	0.903	52 (16.88)	41 (13.31)	0.216	82 (12.35)	86 (12.95)	0.741
Hypertension	274 (77.18)	273 (76.90)	0.929	239 (77.60)	239 (77.60)	1.000	574 (86.45)	575 (86.60)	0.936
Dyslipidemia	263 (74.08)	256 (72.11)	0.554	213 (69.16)	203 (65.91)	0.390	458 (68.98)	452 (68.07)	0.723
Fast glucose (mmol/L)	5.25 (4.85, 5.78)	7.49 (5.97, 10.52)	< 0.001	5.24 (4.86, 5.79)	7.66 (6.02, 10.56)	< 0.001	5.24 (4.84, 5.79)	8.57 (6.26, 11.71)	< 0.001
CACS	0.00 (0.00, 27.55)	12.87 (0.00, 145.79)	< 0.001	0.00 (0.00, 34.71)	34.00 (0.00, 257.59)	< 0.001	0.00 (0.00, 66.40)	113.28 (7.31, 470.36)	< 0.001
CAC category			< 0.001			< 0.001			< 0.001
0	212 (59.72)	139 (39.15)		180 (58.44)	98 (31.82)		357 (53.77)	143 (21.54)
1-100	87 (24.51)	111 (31.27)		72 (23.38)	89 (28.90)		164 (24.70)	174 (26.20)
101-300	32 (9.01)	49 (13.80)		33 (10.71)	51 (16.56)		67 (10.09)	139 (20.93)
> 300	24 (6.76)	56 (15.77)		23 (7.47)	70 (22.73)		76 (11.45)	208 (31.33)
BMD (mg/cm³)	167.53 (145.37, 193.04)	171.70 (148.95, 191.93)	0.430	169.01 (145.01, 189.85)	169.32 (146.29, 185.90)	0.874	163.40 (141.82, 185.09)	166.87 (142.84, 186.62)	0.722
EAT volume (cm³)	149.17 (106.21, 202.46)	157.95 (107.31, 214.17)	0.338	166.60 (126.41, 218.08)	166.26 (114.52, 219.02)	0.495	162.74 (120.21, 213.48)	158.94 (109.21, 213.74)	0.144
EAT density (HU)	-78.71 (-83.49, -74.02)	-76.84 (-83.17, -70.48)	0.006	-80.56 (-85.52, -75.47)	-74.88 (-81.88, -69.48)	< 0.001	-79.95 (-84.58, -75.21)	-74.17 (-80.02, -69.11)	< 0.001

T2DM: Type 2 diabetes mellitus; BMI: Body mass index; CACS: Coronary artery calcium score; CAC: Coronary artery calcification; BMD: Bone mineral density; EAT: Epicardial adipose tissue; HU: Hounsfield unit.

Full Size Table

Citation: Liu YK, Wu FY, Jiang CP, Xia YX, Li Y, Zeng WW, Zhang SY, Fan DN, Zhang MX, Liu TC, Wu XP, Dong Y, Chen W, Zhao YH, Li T, Li Z, Xu XY. Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes. World J Diabetes 2026; 17(8): 121422
URL: https://www.wjgnet.com/1948-9358/full/v17/i8/121422.htm
DOI: https://dx.doi.org/10.4239/wjd.121422

Liu YK, Wu FY, Jiang CP, Xia YX, Li Y, Zeng WW, Zhang SY, Fan DN, Zhang MX, Liu TC, Wu XP, Dong Y, Chen W, Zhao YH, Li T, Li Z, Xu XY. Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes. World J Diabetes 2026; 17(8): 121422 [DOI: 10.4239/wjd.121422]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.