Maternally inherited type 2 diabetes mellitus may be associated with mitochondrial tRNAThr mutations

Table 2 Laboratory assessments of several affected patients with type 2 diabetes mellitus

Subjects	FBG (mmol/L)	FINS (μU/mL)	HOMA-IR	HbA1c (%)	Serum Cr (µmol/L)	eGFR (mL/min)	LDH (U/L)	ALT (U/L)	AST (U/L)	TC (mmol/L)	LDL-C (mmol/L)	HDL-C (mmol/L)
Normal range	3.9-6.1	2.6-12.0	< 2.69	4.0-6.0	57-111	80-130	50-240	9.0-50	15-40	2.85-5.70	1.31-3.37	0.9-1.95
DM-005: II-4	8.0	31.0	11.02	9.2	122	55	255	16	49	3.58	4.55	0.66
DM-005: II-6	7.5	4.88	1.63	6.9	110	63	268	18	55	3.11	5.10	0.81
DM-010: II-1	7.0	13.90	4.32	7.5	76	95	88	29	22	4.25	3.35	1.37
DM-010: II-8	5.1	10.22	2.32	5.0	68	101	92	33	40	4.9	3.10	1.42
DM-010: III-4	4.8	3.50	0.75	5.6	92	122	105	37	43	5.0	2.9	1.28

ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; Cr: Creatinine; DM: Diabetes mellitus; eGFR: Estimated glomerular filtration rate; FBG: Fasting blood glucose; FINS: Fasting insulin; HbA1c: Hemoglobin A1c; HDL: High-density lipoprotein; HOMA-IR: Homeostasis model assessment of insulin resistance; LDH: Lactate dehydrogenase; LDL: Low-density lipoprotein; TC: Total cholesterol.