Regulatory effects of Dangua Fang on the NAMPT/NAD+/SIRT1 axis and amino acid metabolism in type 2 diabetic rats

doi:10.4239/wjd.121202

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Jul 15, 2026; 17(7): 121202
Published online Jul 15, 2026. doi: 10.4239/wjd.121202

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Figure 5 Comparison of amino acid metabolic changes. A: Principal component analysis score scatter plot of all samples; B-D: Principal component analysis score scatter plots and permutation test results of orthogonal projections to latent structures-discriminant analysis models for each comparison group; E: K-means clustering of differential metabolites; F: Hierarchical clustering heatmaps of differential metabolites; G: Classification of differential metabolites. PC1: Principal component 1; PC2: Principal component 2; CON: Control group; MOD: Model group; DFG: Dangua Fang group; MET: Metformin group.

Citation: Han Z, Wang ZT, Yang LQ, Heng XP. Regulatory effects of Dangua Fang on the NAMPT/NAD⁺/SIRT1 axis and amino acid metabolism in type 2 diabetic rats. World J Diabetes 2026; 17(7): 121202
URL: https://www.wjgnet.com/1948-9358/full/v17/i7/121202.htm
DOI: https://dx.doi.org/10.4239/wjd.121202

Han Z, Wang ZT, Yang LQ, Heng XP. Regulatory effects of Dangua Fang on the NAMPT/NAD⁺/SIRT1 axis and amino acid metabolism in type 2 diabetic rats. World J Diabetes 2026; 17(7): 121202 [DOI: 10.4239/wjd.121202]

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