Irisin levels in patients with prediabetes mellitus: A case-control study and meta-analysis

doi:10.4239/wjd.120779

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Jul 15, 2026; 17(7): 120779
Published online Jul 15, 2026. doi: 10.4239/wjd.120779

Table 3 Subgroup analyses of irisin levels

Subgroup	Number of studies	SMD (95%CI)	P value	I² (%)
By specimen type
Plasma	5	-0.769 (-1.304 to -0.234)	0.005	87.0
Serum	5	-0.282 (-0.826 to 0.263)	0.311	87.4
By ELISA kit manufacturer
Adipogen	3	-0.565 (-0.791 to -0.338)	< 0.001	0
Cusabio^TM	1	-0.533 (-0.915 to -0.151)	0.006
Bio Vision, Milpitas	1	-1.307 (-1.774 to -0.840)	< 0.001
Phoenix	1	0.517 (-0.047 to 1.082)	0.072
SinoGeneClon Biontec	1	-0.124 (-0.525 to 0.276)	0.542
USCN Life Science	1	-0.071 (-0.530 to 0.389)	0.763
Not specified (NO)	2	-1.116 (-3.388 to 1.155)	0.335	97.3
Overall	10	-0.524 (-0.897 to -0.152)	0.006	86.7

SMD: Standardized mean difference; 95%CI: 95% confidence interval; ELISA: Enzyme-linked immunosorbent assay.

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Citation: Song LW, Huang WW, Chang LN, Wang X, Sun QQ, Wang XL, He Q. Irisin levels in patients with prediabetes mellitus: A case-control study and meta-analysis. World J Diabetes 2026; 17(7): 120779
URL: https://www.wjgnet.com/1948-9358/full/v17/i7/120779.htm
DOI: https://dx.doi.org/10.4239/wjd.120779

Song LW, Huang WW, Chang LN, Wang X, Sun QQ, Wang XL, He Q. Irisin levels in patients with prediabetes mellitus: A case-control study and meta-analysis. World J Diabetes 2026; 17(7): 120779 [DOI: 10.4239/wjd.120779]

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