Association between the high-sensitivity C-reactive protein-triglyceride-glucose index and metabolic dysfunction-associated steatotic liver disease across different glycemic states

Table 2 Logistic regression analyses the association between C-reactive protein-triglyceride-glucose index and metabolic dysfunction-associated steatotic liver disease

Characteristic	Model 1		Model 2		Model 3
	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
MASLD
CTI (per 1 unit)	5.26 (4.83-5.73)	< 0.001	5.12 (4.49-5.85)	< 0.001	2.74 (1.79-4.20)	< 0.001
CTI quartile
Q1	Ref.	/	Ref.	/	Ref.	/
Q2	3.34 (2.88-3.88)	< 0.001	3.40 (2.72-4.24)	< 0.001	2.59 (1.55-4.32)	< 0.001
Q3	8.98 (7.73-10.5)	< 0.001	8.07 (6.42-10.15)	< 0.001	3.34 (1.85-6.05)	< 0.001
Q4	29.50 (24.70-35.30)	< 0.001	26.40 (19.90-34.90)	< 0.001	5.09 (2.24-11.54)	< 0.001
P for trend		< 0.001		< 0.001		< 0.001

ORs were estimated using the following models: Model 1: Unadjusted for any covariates; Model 2: Additionally adjusted for age, sex, current smoking, current drinking, regular exercise; Model 3: Model 2 + additionally adjusted for systolic blood pressure, diastolic blood pressure, hip circumference, aspartate aminotransferase, total protein, total bilirubin, direct bilirubin, total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol, platelet count, albumin, glycated haemoglobin, estimated glomerular filtration rate, blood urea nitrogen, hypertension, hypertriglyceridemia, low HDL-C. CTI: C-reactive protein-triglyceride-glucose index; MASLD: Metabolic dysfunction-associated steatotic liver disease.