Assessment of the role of general control nonderepressible 2 in gestational diabetes mellitus progression and the underlying mechanisms

Figure 2 General control nonderepressible 2 knockdown improved metabolic parameters in gestational diabetes mellitus mice. A: Body weight; B: Blood glucose and insulin levels; C: Glucose tolerance test; D: Insulin tolerance test; E: Plasma lipid levels. ^aP < 0.05 vs control; ^bP < 0.001 vs control; ^cP < 0.01 vs gestational diabetes mellitus (GDM) + sh-negative control; ^dP < 0.001 vs GDM + sh-negative control. GCN2: General control nonderepressible 2; GDM: Gestational diabetes mellitus; NC: Negative control; TC: Total cholesterol; TG: Triglyceride; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol.