Metabolic feature-based clustering for subtype identification and longitudinal outcome predictions in the Chinese prediabetic population

Figure 3 Cumulative incidence functions (Aalen-Johansen) with adjusted 2-year cumulative incidence function. Panels show Aalen-Johansen cumulative incidence curves for progression to diabetes, regression to normoglycemia, and persistence of prediabetes across the four metabolic subtypes. Shaded bands indicate 95% confidence intervals from 500 bootstrap resamples, and the vertical dotted line marks 2 years. Tables below each panel summarize sample size, events, last event time, unadjusted 2-year cumulative incidence, adjusted 2-year cumulative incidence, and 95% confidence intervals. Adjusted 2-year cumulative incidence was estimated with Fine-Gray competing risk models and marginal standardization, adjusting for subtype, intervention, and sex. MARD: Mild age-related dysmetabolism; MOD: Mild obesity-related dysmetabolism; SID: Severe insulin deficiency; SIR: Severe insulin resistance; CI: Confidence interval.