Visit-to-visit variability of creatinine levels associated with proteinuria progression in Chinese patients with type 2 diabetes mellitus

Figure 3 Subgroup analysis among type 2 diabetes mellitus patients with proteinuria progression identified by urinary albumin-to-creatinine ratio (changed from 30 to 30-299) or (changed from 30-299 to > 300) based on multivariable logistic regression by different variation of metabolic indexes, which was calculated by the percentiles (percentiles 75 and percentiles 67) of their standard deviation among type 2 diabetes mellitus patients. A: Type 2 diabetes mellitus (T2DM) patients with proteinuria progression based on albumin-to-creatinine ratio (ACR) (from < 30 to 30-299) by 75 percentiles of SD; B: T2DM patients with proteinuria progression based on ACR (from < 30 to 30-299) by 67 percentile of SD; C: T2DM patients with proteinuria progression based on ACR (from 30-299 to > 300) by 75 percentile of SD; D: T2DM patients with proteinuria progression based on ACR (from 30-299 to > 300) by 67 percentile of SD. OR: Odds ratios; CI: Confidence intervals; BMI: Body mass index; SBP: Systolic blood pressure; T2DM: Type 2 diabetes mellitus; LDL: Low-density lipoprotein; Cr: Creatinine; GLP-1: Glucagon-like peptide 1; Y: Yes; N: No; P: Percentiles.