Copyright: ©Author(s) 2026.
World J Diabetes. Jun 15, 2026; 17(6): 117524
Published online Jun 15, 2026. doi: 10.4239/wjd.117524
Published online Jun 15, 2026. doi: 10.4239/wjd.117524
Figure 4 Molecular Mechanics/Poisson-Boltzmann Surface Area binding free energy and residue decomposition analysis.
A: Binding free energy decomposition of the formononetin-dihydroorotate dehydrogenase complex, showing major energy components; B: Per-residue free energy contribution analysis, with PHE62, PRO364, LEU42, ALA59, and LEU68 contributing most significantly to binding. MM/PBSA: Molecular Mechanics/Poisson-Boltzmann Surface Area.
- Citation: Tang YT, Chen YP, Yang YN, Liu JL, Wu Q, Zhang S, Pang Q, Wei MY, Gong YB, Ni Q. Shenqi Jiangtang Granules attenuate ferroptosis in diabetic cardiomyopathy via the dihydroorotate dehydrogenase-coenzyme Q pathway. World J Diabetes 2026; 17(6): 117524
- URL: https://www.wjgnet.com/1948-9358/full/v17/i6/117524.htm
- DOI: https://dx.doi.org/10.4239/wjd.117524