Type 2 diabetes, sex and metabolic dysfunction-associated steatotic liver disease

doi:10.4239/wjd.v17.i5.119756

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. May 15, 2026; 17(5): 119756
Published online May 15, 2026. doi: 10.4239/wjd.v17.i5.119756

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Figure 3 Sex-specific risks of cancer and pre-cancerous conditions among individuals with diabetes. Women with diabetes, when compared to men with diabetes, show a 6% increased risk of overall cancer and significantly higher odds for oral, stomach, kidney cancers and leukemia. Diabetes increases the risk of hepatocellular carcinoma (HCC) by 80%, regardless of confounding factors, with men having a higher HCC risk than women. Additionally, both metabolic dysfunction-associated steatotic liver disease and male sex are associated with colorectal adenoma. HCC: Hepatocellular carcinoma; CRA: Colorectal adenoma.

Citation: Lonardo A, Jamalinia M, Weiskirchen R. Type 2 diabetes, sex and metabolic dysfunction-associated steatotic liver disease. World J Diabetes 2026; 17(5): 119756
URL: https://www.wjgnet.com/1948-9358/full/v17/i5/119756.htm
DOI: https://dx.doi.org/10.4239/wjd.v17.i5.119756

Lonardo A, Jamalinia M, Weiskirchen R. Type 2 diabetes, sex and metabolic dysfunction-associated steatotic liver disease. World J Diabetes 2026; 17(5): 119756 [DOI: 10.4239/wjd.v17.i5.119756]

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