Association between high waist-height ratio and endoplasmic reticulum stress of young adults with insulin resistance

Figure 3 Platelets from young individuals with a high waist-to-height ratio have endoplasmic reticulum stress. Cell lysates from platelet-enriched fractions obtained from blood samples of individuals with a waist-to-height ratio (WtHR) < 0.5 (low-WtHR; n = 8) and platelets from participants with a WtHR > 0.5 (high-WtHR; n = 8) were separated by SDS-PAGE and analyzed by immunoblotting. A and B: Bar graphs and representative immunoblots images of total SERCA and Actin expression (A), PERK and pPERK (B). The bar graphs indicate the mean ± SEM. ^aP < 0.005 vs low-waist-to-height ratio group; ^bP < 0.0005 vs low-waist-to-height ratio group. WtHR: Waist-to-height ratio.