Environment and diabetes: Is there an association between the COVID-19 pandemic and phenotypic variation in diabetes?

Table 1 Data across age quartiles in men and women with diabetes, rate ratio in pandemic vs reference cohort (95% confidence interval)

	40-46 years	47-52 years	53-58 years	59-65 years
Men
2-year incidence (per 100000 men)	1.07 (1.01-1.14)	0.97 (0.93-1.02)	0.94 (0.93-1.00)	0.94 (0.90-0.96)
Hypertension	0.81 (0.68-0.94)	0.79 (0.71-0.87)	0.88 (0.83-0.93)	0.92 (0.88-0.96)
Cardiovascular disease	0.82 (0.57-1.07)	0.92 (0.77-1.06)	0.83 (0.73-0.92)	0.94 (0.87-1.01)
Hyperlipidemia	1.11 (0.74-1.47)	0.78 (0.53-1.02)	0.88 (0.69-1.06)	0.92 (0.78-1.06)
Cardiovascular risk factors	0.86 (0.75-0.97)	0.83 (0.76-0.89)	0.86 (0.82-0.91)	0.94 (0.91, 0.97)
ATC class C drugs	0.75 (0.64-0.85)	0.69 (0.47-0.78)	0.54 (0.47-0.61)	0.46 (0.39-0.53)
Mortality rate (1000 person-year)	1.08 (0.58-1.75)	0.89 (0.62-1.28)	1.15 (0.92-1.43)	1.04 (0.89-1.22)
Women
2-year incidence (per 100000 women)	1.00 (0.92-1.09)	0.98 (1.92-1.05)	0.97 (0.92-1.02)	0.94 (0.91-0.98)
Hypertension	0.72 (0.53-0.92)	0.84 (0.73-0.94)	0.86 (0.79-0.93)	0.93 (0.88-0.98)
Cardiovascular disease	1.02 (0.48-1.56)	0.88 (0.54-1.22)	0.93 (0.73-1.13)	0.92 (0.78-1.06)
Hyperlipidemia	1.05 (0.14-1.97)	1.24 (0.79;1.69)	1.14 (0.87-1.42)	0.88 (0.69-1.06)
Cardiovascular risk factors	0.76 (0.59-0.94)	0.87 (0.77-0.96)	0.88 (0.82-0.94)	0.93 (0.89-0.97)
ATC class C drugs	0.64 (0.47-0.82)	0.58 (0.46-0.70)	0.51 (0.41-0.60)	0.40 (0.32-0.49)
Mortality rate (1000 person-year)	0.54 (0.23-1.20)	1.08 (0.69-1.71)	0.92 (0.68-1.24)	1.01 (0.82-1.25)

ATC: Anatomical Therapeutic Chemical.