C1q tumor necrosis factor associated protein 3 protects HaCaT via phosphoinositide 3-kinase/protein kinase B activation by PTEN reduction

Figure 3 C1q tumor necrosis factor associated protein 3 promotes wound healing in diabetic mice. A: The representative images of wound in mice of each group; B: The quantitative analysis of wound size in mice of each group; C: The hematoxylin and eosin staining images of wound tissues in mice of each group; D-F: Serum levels of tumor necrosis factor-α, interleukin (IL)-6, and IL-10 were measured using commercially available enzyme-linked immunosorbent assay kits. ^dP < 0.0001 vs normal group. ^hP < 0.0001 vs diabetes + adenovirus-negative control group. CTRP3: C1q tumor necrosis factor associated protein 3; Ad: Adenovirus; NC: Negative control; TNF: Tumor necrosis factor; IL: Interleukin.