Compound danshen dripping pills for diabetic retinopathy in patients with type 2 diabetes: A superiority, randomized controlled trial

doi:10.4239/wjd.v17.i3.114002

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Diabetes. Mar 15, 2026; 17(3): 114002
Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.114002

Table 5 Subgroup results of efficacy rate, n (%)

Overall efficacy rate	Subgroup	n (CDDP/placebo)	CDDP	Placebo	Between-group difference in overall efficacy rate (95%CI)	Test statistic (CMH)	P value
NPDR severity	Mild	127/48	101 (79.53)	30 (62.5)	0.016-0.324	5.899	0.015
	Moderate	182/56	139 (76.37)	27 (48.21)	0.076-0.341	15.655	< 0.001
	Severe	53/17	39 (73.58)	8 (47.06)	0.000-0.531	1.759	0.185
HbA1c	< 7%	197/64	158 (80.20)	38 (59.38)	0.076-0.341	15.155	< 0.001
HbA1c	≥ 7%	163/55	121 (74.23)	26 (47.27)	0.122-0.418	12.202	< 0.001
Duration of diabetes	< 5 years	57/23	46 (80.70)	13 (56.52)	0.015-0.469	2.963	0.085
Duration of diabetes	≥ 5 years	305/98	233 (76.39)	52 (53.06)	0.124-0.343	18.615	< 0.001

NPDR: Non-proliferative diabetic retinopathy; CDDP: Compound danshen dripping pill; CMH: Cochran-Mantel-Haenszel.

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Citation: An XD, Zhang GL, Zhang YH, Jin D, Ji HY, Wei LJ, He YL, Zheng YL, Li DJ, Wu XW, Li YB, Zhou J, Tan SJ, Zhang MC, Fan K, Lu S, Yu JS, Wang YL, Chen SJ, Liu QH, Jin M, Wu L, Lian FM, Tong XL. Compound danshen dripping pills for diabetic retinopathy in patients with type 2 diabetes: A superiority, randomized controlled trial. World J Diabetes 2026; 17(3): 114002
URL: https://www.wjgnet.com/1948-9358/full/v17/i3/114002.htm
DOI: https://dx.doi.org/10.4239/wjd.v17.i3.114002

An XD, Zhang GL, Zhang YH, Jin D, Ji HY, Wei LJ, He YL, Zheng YL, Li DJ, Wu XW, Li YB, Zhou J, Tan SJ, Zhang MC, Fan K, Lu S, Yu JS, Wang YL, Chen SJ, Liu QH, Jin M, Wu L, Lian FM, Tong XL. Compound danshen dripping pills for diabetic retinopathy in patients with type 2 diabetes: A superiority, randomized controlled trial. World J Diabetes 2026; 17(3): 114002 [DOI: 10.4239/wjd.v17.i3.114002]

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