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Copyright: ©Author(s) 2026.
World J Diabetes. Mar 15, 2026; 17(3): 114002
Published online Mar 15, 2026. doi: 10.4239/wjd.v17.i3.114002
Table 3 Changes in bead-like, intraretinal microvascular abnormality and fundus neovascularization, n (%)

CDDP (n = 362)
Placebo (n = 121)
P value
Bead-like
Baseline> 0.999
None356 (98.34)119 (98.35)
Present6 (1.66)2 (1.65)
12 weeks> 0.999
None356 (98.34)119 (98.35)
Present6 (1.66)2 (1.65)
24 weeks> 0.999
None356 (98.34)119 (98.35)
Present6 (1.66)2 (1.65)
Intraretinal microvascular abnormalities
Baseline0.578
No abnormality306 (84.53)102 (84.30)
Mild abnormality31 (8.56)7 (5.79)
Severe abnormality25 (6.91)12 (9.92)
12 weeks0.716
No abnormality305 (84.25)104 (85.96)
Mild abnormality32 (8.84)5 (4.13)
Severe abnormality25 (6.91)12 (9.92)
24 weeks0.394
No abnormality305 (84.25)100 (82.64)
Mild abnormality30 (8.29)9 (7.44)
Severe abnormality27 (7.46)12 (9.92)
Fundus neovascularization
Baseline
None362 (100)121 (100)
Present0 (0.00)0 (0.00)
12 weeks0.999
None360 (99.45)120 (99.17)
Present2 (0.55)1 (0.83)
24 weeks0.999
None360 (99.45)120 (99.17)
Present2 (0.55)1 (0.83)


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