Compound danshen dripping pills for diabetic retinopathy in patients with type 2 diabetes: A superiority, randomized controlled trial

Table 1 Detailed criteria for efficacy determination

Grading	FFA scale	Hemorrhage	Effusion (reference)
Marked effectiveness	Improvement in at least one evaluation point	Reduced > 50%	Absent/stable/reduced
	Improvement in at least 2 evaluation points	Absent/stable	Absent/stable/reduced
Effectiveness	Improvement in at least one evaluation point	Reduced ≤ 50%	Absent/stable/reduced
	Improvement in at least one evaluation point	Absent/stable	Absent/stable/reduced
	Stable	Reduced < 50%	Absent/stable/reduced
	Stable	Stable	Reduced ≥ 50%
Stability	Patients not meeting the criteria for marked effectiveness, effectiveness, or worsening
Worsening	Occurrence of worsening in one or more evaluation points	Increased	Absent/stable/increased
	Occurrence of worsening in two or more evaluation points	Absent/stable	Absent/stable/increased
	Or occurrence of IRMA/neovascularization/venous beading
	Stable	Increased	Absent/stable/increased
	Stable	Stable	Increased ≥ 50%

FFA: Fundus fluorescein angiography; IRMA: Intraretinal microvascular abnormalities.