Amomum villosum extract alleviates diabetic neuropathy via phosphoinositide 3-kinase/AKT-mediated antioxidative and anti-apoptotic effects

Figure 2 Diabetic rats treated with Amomum villosum Lour. had higher mechanical and thermal pain thresholds. A: Mechanical sensitivity of rats was assessed by stimulating with von Frey nylon filaments, with the withdrawal response of the paw being observed; B: Thermal sensitivity was assessed using the hot plate method, with paw withdrawal latency serving as the indicator of thermal pain threshold. ^aP < 0.05 diabetes mellitus (DM) + vehicle group vs control group. AVL: Amomum villosum Lour.