Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

Figure 5 Effects of polyherbal extract on the protein expression of pro-inflammatory cytokines. A: Tumour necrosis factor-α; B: Interleukin-1β. The diabetic group exhibited a significant decrease in tumour necrosis factor-α and interleukin-1β levels compared with the control group. The administration of polyherbal extract significantly attenuated the activities of these markers in the diabetic + polyherbal extract group compared with the diabetic group. Data are expressed as mean ± SEM (n = 7). ^cP < 0.001 vs control group, ^eP < 0.01 vs diabetic group, ^fP < 0.001 vs diabetic group. Met: Metformin; PHE: Polyherbal extract; TNF-α: Tumour necrosis factor-α; IL-1β: Interleukin-1β.