Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

Figure 4 The diabetic group exhibited significant alterations in the activities of antioxidant enzymes (glutathione-S-transferase, superoxide dismutase, and catalase) compared with the control group. A: Glutathione-S-transferase; B: Superoxide dismutase; C: Catalase. The administration of polyherbal extract significantly attenuated the activities of these enzymes in the diabetic + polyherbal extract group compared with the diabetic group. ^cP < 0.001 vs control group, ^dP < 0.05 vs diabetic group, ^eP < 0.01 vs diabetic group, and ^fP < 0.001 vs diabetic group. CDNB: 1-Chloro-2,4-dinitrobenzene; Met: Metformin; PHE: Polyherbal extract.