Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

Figure 3 Effect of polyherbal extract supplementation. A: On the malondialdehyde (MDA) level. The diabetic group showed a significant increase in the MDA level compared with the control group. Polyherbal extract (PHE) supplementation significantly decreased the MDA level in the diabetic + PHE group compared with the diabetic group; B: On the reduced glutathione (GSH) level. The diabetic group showed a significant decrease in the GSH content compared with the control group. PHE supplementation significantly increased the GSH content in the diabetic + PHE group compared with the diabetic group. Data are expressed as mean ± SEM (n = 7). ^cP < 0.001 vs control group, ^dP < 0.05 vs diabetic group, ^eP < 0.01 vs diabetic group, ^fP < 0.001 vs diabetic group. Met: Metformin; PHE: Polyherbal extract; MDA: Malondialdehyde.