Neuroprotective potential of a plant-based intervention in diabetic neuropathy: Biochemical and behavioral insights from a streptozotocin-induced rat model

Table 4 Effect of polyherbal extract on quantitative histopathological changes in the pancreas and sciatic nerve tissue, mean ± SEM

Groups	Number of islets, 10 × field	Diameter of the islet	Sciatic nerve damage score
Control	6.33 ± 0.29	163.62 ± 12.71	0.0 ± 0.0
Diabetic	3.7 ± 0.32a	95.83 ± 5.10a	2.85 ± 0.16a
Diabetic+ PHE	4.6 ± 0.42d	145.81 ± 6.32d	1.62 ± 0.23d
Diabetic + Met	4.9 ± 0.52d	140.22 ± 6.72d	1.59 ± 0.24d
Control + PHE	5.89 ± 0.37	156.47 ± 8.90	0.12 ± 0.02

^aP < 0.05 vs control group.

^dP < 0.05 vs diabetic group.

PHE: Polyherbal extract; Met: Metformin.