Association of serum bile acid profiles with the risk of gastrointestinal autonomic neuropathy in patients with type 2 diabetes mellitus

Figure 3 Spearman’s correlation analysis among bile acids, clinical indicators, and Gastrointestinal Symptom Rating Scale scores in the diabetic gastric autonomic neuropathy group. A: Correlations among clinical indicators, bile acid levels, and Gastrointestinal Symptom Rating Scale scores in the type 2 diabetes mellitus and diabetic gastric autonomic neuropathy groups; B-E: Scatter plots depicting the correlations among clinical indicators, bile acids, and the scores of gastrointestinal symptoms. ^aP < 0.05; ^bP < 0.01. GSRS: Gastrointestinal Symptom Rating Scale; eGFR: Estimated glomerular filtration rate; PLT: Platelets; LDL-C: Low-density lipoprotein cholesterol; TC: Total cholesterol; TG: Triglycerides; SBP: Systolic blood pressure; DBP: Diastolic blood pressure; UACR: Urinary albumin-to-creatinine ratio; 2hC-P: 2-hour c-peptide; C-P: C-peptide; HDL-C: High-density lipoprotein cholesterol; T2DM: Type 2 diabetes mellitus; GI: Gastrointestinal; CA: Cholic acid; UDCA: Ursodeoxycholic acid; CDCA: Chenodeoxycholic acid; DCA: Deoxycholic acid; SCr: Serum creatinine; BUN: Blood urea nitrogen; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; ALB: Albumin; BMI: Body mass index; CRP: C-reactive protein; Hb: Hemoglobin; GUDCA: Glycoursodeoxycholic acid; GCDCA: Glycochenodeoxycholic acid; LCA: Lithocholic acid; HbA1c: Hemoglobin a1c; FBG: Fasting blood glucose; GDCA: Glycodeoxycholic acid; GLCA: Glycolithocholic acid; TLCA: Taurolithocholic acid; TDCA: Taurodeoxycholic acid; TCDCA: Taurochenodeoxycholic acid; GCA: Glycocholic acid; TCA: Taurocholic acid; TUDCA: Tauroursodeoxycholic acid.